diff --git a/embassy-stm32/build.rs b/embassy-stm32/build.rs
index a4709f4c..ddfa97b2 100644
--- a/embassy-stm32/build.rs
+++ b/embassy-stm32/build.rs
@@ -244,11 +244,13 @@ fn main() {
         (("usart", "CTS"), quote!(crate::usart::CtsPin)),
         (("usart", "RTS"), quote!(crate::usart::RtsPin)),
         (("usart", "CK"), quote!(crate::usart::CkPin)),
+        (("usart", "DE"), quote!(crate::usart::DePin)),
         (("lpuart", "TX"), quote!(crate::usart::TxPin)),
         (("lpuart", "RX"), quote!(crate::usart::RxPin)),
         (("lpuart", "CTS"), quote!(crate::usart::CtsPin)),
         (("lpuart", "RTS"), quote!(crate::usart::RtsPin)),
         (("lpuart", "CK"), quote!(crate::usart::CkPin)),
+        (("lpuart", "DE"), quote!(crate::usart::DePin)),
         (("spi", "SCK"), quote!(crate::spi::SckPin)),
         (("spi", "MOSI"), quote!(crate::spi::MosiPin)),
         (("spi", "MISO"), quote!(crate::spi::MisoPin)),
diff --git a/embassy-stm32/src/usart/buffered.rs b/embassy-stm32/src/usart/buffered.rs
index d024bedc..874af1d7 100644
--- a/embassy-stm32/src/usart/buffered.rs
+++ b/embassy-stm32/src/usart/buffered.rs
@@ -89,6 +89,33 @@ impl<'d, T: BasicInstance> BufferedUart<'d, T> {
         Self::new_inner(state, peri, rx, tx, irq, tx_buffer, rx_buffer, config)
     }
 
+    #[cfg(not(usart_v1))]
+    pub fn new_with_de(
+        state: &'d mut State<'d, T>,
+        peri: impl Peripheral<P = T> + 'd,
+        rx: impl Peripheral<P = impl RxPin<T>> + 'd,
+        tx: impl Peripheral<P = impl TxPin<T>> + 'd,
+        irq: impl Peripheral<P = T::Interrupt> + 'd,
+        de: impl Peripheral<P = impl DePin<T>> + 'd,
+        tx_buffer: &'d mut [u8],
+        rx_buffer: &'d mut [u8],
+        config: Config,
+    ) -> BufferedUart<'d, T> {
+        into_ref!(de);
+
+        T::enable();
+        T::reset();
+
+        unsafe {
+            de.set_as_af(de.af_num(), AFType::OutputPushPull);
+            T::regs().cr3().write(|w| {
+                w.set_dem(true);
+            });
+        }
+
+        Self::new_inner(state, peri, rx, tx, irq, tx_buffer, rx_buffer, config)
+    }
+
     fn new_inner(
         state: &'d mut State<'d, T>,
         _peri: impl Peripheral<P = T> + 'd,
diff --git a/embassy-stm32/src/usart/mod.rs b/embassy-stm32/src/usart/mod.rs
index aea054a4..ea75361f 100644
--- a/embassy-stm32/src/usart/mod.rs
+++ b/embassy-stm32/src/usart/mod.rs
@@ -646,6 +646,31 @@ impl<'d, T: BasicInstance, TxDma, RxDma> Uart<'d, T, TxDma, RxDma> {
         Self::new_inner(peri, rx, tx, irq, tx_dma, rx_dma, config)
     }
 
+    #[cfg(not(usart_v1))]
+    pub fn new_with_de(
+        peri: impl Peripheral<P = T> + 'd,
+        rx: impl Peripheral<P = impl RxPin<T>> + 'd,
+        tx: impl Peripheral<P = impl TxPin<T>> + 'd,
+        irq: impl Peripheral<P = T::Interrupt> + 'd,
+        de: impl Peripheral<P = impl DePin<T>> + 'd,
+        tx_dma: impl Peripheral<P = TxDma> + 'd,
+        rx_dma: impl Peripheral<P = RxDma> + 'd,
+        config: Config,
+    ) -> Self {
+        into_ref!(de);
+
+        T::enable();
+        T::reset();
+
+        unsafe {
+            de.set_as_af(de.af_num(), AFType::OutputPushPull);
+            T::regs().cr3().write(|w| {
+                w.set_dem(true);
+            });
+        }
+        Self::new_inner(peri, rx, tx, irq, tx_dma, rx_dma, config)
+    }
+
     fn new_inner(
         peri: impl Peripheral<P = T> + 'd,
         rx: impl Peripheral<P = impl RxPin<T>> + 'd,
@@ -1040,6 +1065,7 @@ pin_trait!(TxPin, BasicInstance);
 pin_trait!(CtsPin, BasicInstance);
 pin_trait!(RtsPin, BasicInstance);
 pin_trait!(CkPin, BasicInstance);
+pin_trait!(DePin, BasicInstance);
 
 dma_trait!(TxDma, BasicInstance);
 dma_trait!(RxDma, BasicInstance);